Cyclic GMP alterations in fetal rat cerebrum after global intrauterine ischemia: Role of guanylate cyclase phosphorylation

@article{Magal1990CyclicGA,
  title={Cyclic GMP alterations in fetal rat cerebrum after global intrauterine ischemia: Role of guanylate cyclase phosphorylation},
  author={Ella Magal and Jean Zwiller and M O Revel and Ephraim Yavin and J Louis},
  journal={Journal of Molecular Neuroscience},
  year={1990},
  volume={2},
  pages={91-99}
}
Changes in the levels of cyclic AMP (cAMP) and cyclic GMP (cGMP) have been measured in brains of 20-day-old rat fetuses exposed to global intrauterine ischemia. Ischemia of different duration (0.5–30 minutes) did not alter the level of cAMP. In contrast, cGMP levels increased as a result of ischemia. This increase was seen even after a short period of… CONTINUE READING