Cyclic Dinucleotides in Oral Bacteria and in Oral Biofilms

  title={Cyclic Dinucleotides in Oral Bacteria and in Oral Biofilms},
  author={Ulvi Kahraman G{\"u}rsoy and Mervi G{\"u}rsoy and Eija K{\"o}n{\"o}nen and Herman O. Sintim},
  journal={Frontiers in Cellular and Infection Microbiology},
Oral cavity acts as a reservoir of bacterial pathogens for systemic infections and several oral microorganisms have been linked to systemic diseases. Quorum sensing and cyclic dinucleotides, two “decision-making” signaling systems, communicate to regulate physiological process in bacteria. Discovery of cyclic dinucleotides has a long history, but the progress in our understanding of how cyclic dinucleotides regulate bacterial lifestyle is relatively new. Oral microorganisms form some of the… 

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