Cyclic AMP-mediated induction of the glial fibrillary acidic protein is independent of protein kinase A activation in rat C6 glioma.

@article{Anciaux1997CyclicAI,
  title={Cyclic AMP-mediated induction of the glial fibrillary acidic protein is independent of protein kinase A activation in rat C6 glioma.},
  author={Katelijne Anciaux and K Van Dommelen and Supergravity H. Nicolai and E Van Mechelen and Herman Slegers},
  journal={Journal of neuroscience research},
  year={1997},
  volume={48 4},
  pages={324-33}
}
N6-O'2-dibutyryl cAMP (dbcAMP), N6-monobutyryl cAMP (N6-mbcAMP), 8-Chloro cAMP (ClcAMP), and O'2-monobutyryl cAMP (O'2-mbcAMP) were used to study glial fibrillary acidic protein (GFAP) induction in rat C6 glioma. With the exception of O'2-mbcAMP, these cAMP analogs induced GFAP after stimulation of cells with a concentration of 0.5-1 mM. Only dbcAMP and N6… CONTINUE READING