Cyclic AMP-dependent protein kinase interferes with GTP gamma S stimulated IP3 formation in differentiated HL-60 cell membranes.

@article{Misaki1989CyclicAP,
  title={Cyclic AMP-dependent protein kinase interferes with GTP gamma S stimulated IP3 formation in differentiated HL-60 cell membranes.},
  author={N Misaki and Toshihiro Imaizumi and Yoshinori Watanabe},
  journal={Life sciences},
  year={1989},
  volume={45 18},
  pages={
          1671-8
        }
}
The effects of addition of activated cyclic AMP-dependent protein kinase (PKA) on the function of islet-activating protein (IAP)-sensitive GTP-binding (G) protein were studied in the plasma membranes of 3H-inositol-labeled differentiated human leukemic (HL-60) cells. Pretreatment of the membranes with activated PKA (0.1 mg/ml) in the presence of MgATP for… CONTINUE READING