Cyclic AMP and protein kinase A stimulate Cdc42: role of A(2) adenosine receptors in human mast cells.

@article{Feoktistov2000CyclicAA,
  title={Cyclic AMP and protein kinase A stimulate Cdc42: role of A(2) adenosine receptors in human mast cells.},
  author={I. A. Feoktistov and Anna E. Goldstein and Italo Biaggioni},
  journal={Molecular pharmacology},
  year={2000},
  volume={58 5},
  pages={903-10}
}
The functional activity of Cdc42 is known to be regulated by proteins that control its GDP/GTP-bound state. However, there is still limited information on how Cdc42 is controlled by G-protein-coupled receptors. Adenosine receptors belong to the G-protein-coupled receptor family of cell surface receptors. Human HMC-1 mast cells express the high-affinity A(2A… CONTINUE READING