Cyclic AMP and its receptor protein are required for expression of transfer genes of conjugative plasmid F in Escherichia coli


A number of cya and crp mutants of Escherichia coli HfrH were analyzed for several Tra functions of the F plasmid. The mutants were observed to be deficient in conjugal donor ability, absorption of phages MS2 and Qβ and surface exclusion. These defects were suppressed in cya mutants grown with cAMP supplementation. A cAMP concentration of 3×10-4 M produced… (More)
DOI: 10.1007/BF00330320


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