Cyclic AMP and cyclic GMP activate protein kinase G in cavernosal smooth muscle cells: old age is a negative factor.

Abstract

OBJECTIVE To investigate protein kinase G-I (PKG-I) expression and activation in cavernosal smooth muscle cells (CSMC) of young and old rats. MATERIALS AND METHODS PKG-I expression in rat penis was examined by immunohistochemical staining, reverse transcription-polymerase chain reaction, and Western blot analysis. CSMC isolated from young (16-week-old… (More)

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@article{Lin2002CyclicAA, title={Cyclic AMP and cyclic GMP activate protein kinase G in cavernosal smooth muscle cells: old age is a negative factor.}, author={C S Lin and Xuyang Liu and Selwyn S Chow and T F Lue}, journal={BJU international}, year={2002}, volume={89 6}, pages={576-82} }