Cyclic AMP and alkaline pH downregulate carbonic anhydrase 2 in mouse fibroblasts.

Abstract

BACKGROUND The hydration of CO2 catalyzed by the ubiquitous carbonic anhydrase 2 (Ca2) is central for bicarbonate transport, bone metabolism and acid-base homeostasis in metazoans. There is evidence that in some tissues Ca2 expression can be acutely induced by cAMP, whereas in other cell types it is unresponsive to cAMP-mediated transcriptional activation… (More)
DOI: 10.1016/j.bbagen.2013.12.015

Topics

Cite this paper

@article{Mardones2014CyclicAA, title={Cyclic AMP and alkaline pH downregulate carbonic anhydrase 2 in mouse fibroblasts.}, author={Pablo Mardones and Jung Chin Chang and Ronald P. J. Oude Elferink}, journal={Biochimica et biophysica acta}, year={2014}, volume={1840 6}, pages={1765-70} }