Cyanobacterium producing cylindrospermopsin cause oxidative stress at environmentally relevant concentrations in sub-chronically exposed tilapia (Oreochromis niloticus).

@article{GuzmnGuilln2013CyanobacteriumPC,
  title={Cyanobacterium producing cylindrospermopsin cause oxidative stress at environmentally relevant concentrations in sub-chronically exposed tilapia (Oreochromis niloticus).},
  author={Remedios Guzm{\'a}n-Guill{\'e}n and Ana Isabel Prieto and Vitor Vasconcelos and Ana M Came{\'a}n},
  journal={Chemosphere},
  year={2013},
  volume={90 3},
  pages={1184-94}
}
Cylindrospermopsin (CYN) is a potent cyanobacterial cytotoxin produced by certain freshwater cyanobacteria. Structurally, it is an alkaloid with a tricyclic guanidine moiety combined with hydroxymethyluracil. It has proved to be a potent inhibitor of protein synthesis, and to deplete hepatic glutathione. Recently, some studies have shown that CYN produces changes in some oxidative stress biomarkers in fish acutely exposed to pure CYN by oral and intraperitoneal (i.p.) routes. In the present… CONTINUE READING