Cyanide antidotes for mass casualties: water-soluble salts of the dithiane (sulfanegen) from 3-mercaptopyruvate for intramuscular administration.

@article{Patterson2013CyanideAF,
  title={Cyanide antidotes for mass casualties: water-soluble salts of the dithiane (sulfanegen) from 3-mercaptopyruvate for intramuscular administration.},
  author={Steven E. Patterson and Alexandre R. Monteil and Jonathan F. Cohen and Daune L. Crankshaw and Robert Vince and Herbert T. Nagasawa},
  journal={Journal of medicinal chemistry},
  year={2013},
  volume={56 3},
  pages={
          1346-9
        }
}
Current cyanide antidotes are administered by IV infusion, which is suboptimal for mass casualties. Therefore, in a cyanide disaster, intramuscular (IM) injectable antidotes would be more appropriate. We report the discovery of the highly water-soluble sulfanegen triethanolamine as a promising lead for development as an IM injectable cyanide antidote. 

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