Cyanamide reduces brain catalase and ethanol-induced locomotor activity: is there a functional link?

@article{SanchisSegura1999CyanamideRB,
  title={Cyanamide reduces brain catalase and ethanol-induced locomotor activity: is there a functional link?},
  author={Carles Sanchis-Segura and Marta Miquel and Merc{\'e} Correa and Carlos M. G. Aragon},
  journal={Psychopharmacology},
  year={1999},
  volume={144},
  pages={83-89}
}
The present study was designed in an attempt to assess a previously suggested role of brain catalase activity in ethanol-induced behaviour by examining ethanol-induced locomotor activity in cyanamide-treated mice. Mice were pretreated with IP injections of the catalase inhibitor cyanamide (3.75, 7.5, 15, 30 or 45 mg/kg) or saline. Following this treatment, animals in each group received IP injections of ethanol (0.0, 1.6, 2.4 or 3.2 g/kg) and locomotion was recorded. Several time intervals (0… CONTINUE READING