CyTargetLinker: A Cytoscape App to Integrate Regulatory Interactions in Network Analysis

  title={CyTargetLinker: A Cytoscape App to Integrate Regulatory Interactions in Network Analysis},
  author={Martina Kutmon and Thomas Kelder and Pooja R Mandaviya and Chris T. A. Evelo and Susan L. Coort},
  booktitle={PloS one},
INTRODUCTION The high complexity and dynamic nature of the regulation of gene expression, protein synthesis, and protein activity pose a challenge to fully understand the cellular machinery. By deciphering the role of important players, including transcription factors, microRNAs, or small molecules, a better understanding of key regulatory processes can be obtained. Various databases contain information on the interactions of regulators with their targets for different organisms, data recently… CONTINUE READING
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