Cutting edge: programmed death-1 defines CD8+CD122+ T cells as regulatory versus memory T cells.


Recent convincing data have shown that naturally occurring CD8(+)CD122(+) T cells are also regulatory T cells. Paradoxically, CD8(+)CD122(+) T cells have been well described as memory T cells. Given their critical role in tolerance versus long-term immunity, it is important to reconcile this profound dichotomy. In this study, we reported that CD8(+)CD122… (More)
DOI: 10.4049/jimmunol.1000661


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