Cutting edge: Vitamin D regulates lipid metabolism in Mycobacterium tuberculosis infection.

  title={Cutting edge: Vitamin D regulates lipid metabolism in Mycobacterium tuberculosis infection.},
  author={Hugh Salamon and Natalie Bruiners and Karim Lakehal and Lanbo Shi and Janani Ravi and Ken D. Yamaguchi and Richard Pine and Maria Laura Gennaro},
  journal={Journal of immunology},
  volume={193 1},
Vitamin D has long been linked to resistance to tuberculosis, an infectious respiratory disease that is increasingly hard to treat because of multidrug resistance. Previous work established that vitamin D induces macrophage antimicrobial functions against Mycobacterium tuberculosis. In this article, we report a novel, metabolic role for vitamin D in tuberculosis identified through integrated transcriptome and mechanistic studies. Transcriptome analysis revealed an association between vitamin D… CONTINUE READING
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