Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types.

  title={Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types.},
  author={Laure Dumoutier and Caroline Leemans and Diane Lejeune and Sergei V. Kotenko and Jean-Christophe Renauld},
  journal={Journal of immunology},
  volume={167 7},
IL-10-related cytokines include IL-20 and IL-22, which induce, respectively, keratinocyte proliferation and acute phase production by hepatocytes, as well as IL-19, melanoma differentiation-associated gene 7, and AK155, three cytokines for which no activity nor receptor complex has been described thus far. Here, we show that mda-7 and IL-19 bind to the previously described IL-20R complex, composed by cytokine receptor family 2-8/IL-20Ralpha and DIRS1/IL-20Rbeta (type I IL-20R). In addition, mda… CONTINUE READING
Highly Influential
This paper has highly influenced 18 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 142 extracted citations

IL-19 is a component of the pathogenetic IL-23/IL-17 cascade in psoriasis.

The Journal of investigative dermatology • 2014
View 4 Excerpts
Highly Influenced

Anti-Inflammatory Effects of Interleukin-19 in Vascular Disease

International journal of inflammation • 2012
View 5 Excerpts
Highly Influenced

IL-24: a classic cytokine and/or a potential cure for cancer?

Journal of cellular and molecular medicine • 2008
View 4 Excerpts
Highly Influenced

Estrogen promotes the growth of decidual stromal cells in human early pregnancy.

Molecular human reproduction • 2013
View 4 Excerpts
Highly Influenced

Interleukin-19 in Breast Cancer

Clinical & developmental immunology • 2013
View 7 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…