Cutting Edge : Egress of Newly Generated Plasma Cells from Peripheral Lymph Nodes Depends on 2 Integrin 1

Abstract

During humoral immune responses, naive B cells differentiate into Ab-secreting plasma cells within secondary lymphoid organs. Differentiating plasma cells egress from their sites of generation and redistribute to other tissues, predominantly the bone marrow and mucosal tissues. In this study, we demonstrate that within peripheral lymph nodes newly generated… (More)

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