Cutting Edge: Immunological consequences and trafficking of human regulatory macrophages administered to renal transplant recipients.

@article{Hutchinson2011CuttingEI,
  title={Cutting Edge: Immunological consequences and trafficking of human regulatory macrophages administered to renal transplant recipients.},
  author={James A. Hutchinson and Paloma Riquelme and B Sawitzki and Stefan Tomiuk and Patrick Miqueu and Maaz Zuhayra and Hans Heinrich Oberg and Andreas Pascher and Ulf Luetzen and Uwe Janssen and Christiane Broichhausen and Lutz Renders and Friedrich Thaiss and Ernst H Scheuermann and Eberhard Henze and H P Volk and Lucienne Chatenoud and R. Lechler and Kathryn J. Wood and Dieter Kabelitz and Hans J. Schlitt and Edward Kenneth Geissler and Fred Faendrich},
  journal={Journal of immunology},
  year={2011},
  volume={187 5},
  pages={2072-8}
}
Regulatory macrophages (M regs) were administered to two living-donor renal transplant recipients. Both patients were minimized to low-dose tacrolimus monotherapy within 24 wk of transplantation and subsequently maintained excellent graft function. After central venous administration, most M regs remained viable and were seen to traffic from the pulmonary… CONTINUE READING