Cutoff Scanning Matrix (CSM): structural classification and function prediction by protein inter-residue distance patterns

@inproceedings{Pires2011CutoffSM,
  title={Cutoff Scanning Matrix (CSM): structural classification and function prediction by protein inter-residue distance patterns},
  author={Douglas E V Pires and Raquel Cardoso de Melo-Minardi and Marcos Augusto dos Santos and Carlos Henrique da Silveira and Marcelo M. Santoro and Wagner Meira},
  booktitle={BMC Genomics},
  year={2011}
}
The unforgiving pace of growth of available biological data has increased the demand for efficient and scalable paradigms, models and methodologies for automatic annotation. In this paper, we present a novel structure-based protein function prediction and structural classification method: Cutoff Scanning Matrix (CSM). CSM generates feature vectors that represent distance patterns between protein residues. These feature vectors are then used as evidence for classification. Singular value… CONTINUE READING
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