Cutibacterium (Formerly Propionibacterium) avidum: A Rare but Avid Agent of Prosthetic Hip Infection.

@article{Zeller2018CutibacteriumP,
  title={Cutibacterium (Formerly Propionibacterium) avidum: A Rare but Avid Agent of Prosthetic Hip Infection.},
  author={Valérie Zeller and Val{\'e}rie-Anne Letembet and Vanina Meyssonnier and Béate Heym and Jean Marc Ziza and Simon Marmor},
  journal={The Journal of arthroplasty},
  year={2018},
  volume={33 7},
  pages={
          2246-2250
        }
}

Simultaneous Propionibacterium avidum and Propionibacterium acnes Chronic Periprosthetic Hip Joint Infection: A Case Report

TLDR
A case of a 77-year-old diabetic overweight male patient who developed a periprosthetic hip infection due to P. avidum and P. acnes is reported, which represents the first case of chronic periprothetic hip joint co-infection.

Association of Cutibacterium avidum Colonization in the Groin With Obesity: A Potential Risk Factor for Hip Periprosthetic Joint Infection

TLDR
The groin, rather than the anterior thigh, showed colonization for C. avidum in obese patients, and increased BMI was associated with colonization at the groin.

Clinical and Biological Features of Cutibacterium (Formerly Propionibacterium) avidum, an Underrecognized Microorganism

  • S. Corvec
  • Biology
    Clinical Microbiology Reviews
  • 2018
TLDR
These analyses have revealed that C. avidum causes diverse diseases mediated by multiple virulence factors, and specific genomic regions within this species that are involved in adherence and biofilm formation as well as fitness, survival, and defense functions are revealed.

Cutibacterium avidum resists surgical skin antisepsis in the groin—a potential risk factor for periprosthetic joint infection: a quality control study

TLDR
Whether standard skin antisepsis with povidone-iodine/alcohol before total hip arthroplasty (THA) is effective to eliminate colonizing bacteria with focus on C. avidum is addressed and might pose an increased risk for PJI when considering a THA.

Orthopedic implant-associated infections caused by Cutibacterium spp. – A remaining diagnostic challenge

TLDR
Cutibacterium IAI was diagnosed late in the disease course and presented with subtle signs, and prolonged culture incubation and implant sonication improved the poor performance of conventional microbiological tests.

The impact of surgical strategy and rifampin on treatment outcome in Cutibacterium periprosthetic joint infections.

TLDR
It is concluded that a rifampin combination is not markedly superior in Cutibacterium PJI but a dedicated prospective multicenter study is needed.

Cutibacterium colonization of the anterior and lateral thigh.

TLDR
Findings were not statistically significant, but alternative skin preparations for total hip arthroplasty should be considered, given the high colonization rate of Cutibacterium.

References

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Propionibacterium avidum as an Etiological Agent of Prosthetic Hip Joint Infection

TLDR
Skin incision in close proximity to the groin or deep skin crease, such as the anteriorly curved skin incision approach, might pose a risk of PJIs by P. avidum, especially in obese patients.

Treatment of prosthetic joint infections due to Propionibacterium

TLDR
Propionibacterium-associated PJI treated with surgery in combination with long-term antibiotic administration had a successful outcome at 1- and 2-year follow-up irrespective of whether the patient was treated with rifampicin.

Propionibacterium avidum infection following breast reduction: high morbidity from a low-virulence pathogen

TLDR
A 36-year-old woman with a rare case of P. avidum breast abscess, causing severe morbidity following breast reduction surgery, presented with a non-painful wound discharge 3 weeks postoperatively, and was treated conservatively.

[Propionibacterium avidum cutaneous abscess in a young immunocompetent].

TLDR
To the authors' knowledge, this is only the third documented case of infection by this organism in immunocompetent patient without iatrogenic risk, and further studies on the pathogenicity of P. avidum are more than necessary.

Propionibacterium avidum sacroiliitis and osteomyelitis.

TLDR
A case of P. avidum sacroilitis, psoas abscess and osteomyelitis in a 67-year-old male who had recently undergone surgical repair of an inguinal hernia is reported and infection by Propionibacterium spp.

Propionibacterium acnes: from Commensal to Opportunistic Biofilm-Associated Implant Pathogen

TLDR
Treatment requires a combination of surgery and a prolonged antibiotic treatment regimen to successfully eliminate the remaining bacteria, and most authors suggest a course of 3 to 6 months of antibiotic treatment, including 2 to 6 weeks of intravenous treatment with a beta-lactam.