Cutaneous nerves in cafe au lait spots with white halos in infants with neurofibromatosis. An electron microscopic study.

@article{Mihara1992CutaneousNI,
  title={Cutaneous nerves in cafe au lait spots with white halos in infants with neurofibromatosis. An electron microscopic study.},
  author={Motoyuki Mihara and Hiroko Nakayama and Tuba Aki and Tomoaki Inoue and Satoshi Shimao},
  journal={Archives of dermatology},
  year={1992},
  volume={128 7},
  pages={957-61}
}
BACKGROUND AND DESIGN Although two cardinal skin manifestations of neurofibromatosis are cutaneous neurofibromas and cafe au lait spots, the pathogenesis of cafe au lait spots are very poorly known compared with that of cutaneous neurofibromas. Thus, the cafe au lait spots in two Japanese infants were clinically, histologically, and electron-microscopically investigated. OBSERVATIONS Some of the cafe au lait spots in the mongolian spots were surrounded by white halos. Histologically, in the… CONTINUE READING