Cutaneous lesions showing giant yeast forms of Blastomyces dermatitidis

  title={Cutaneous lesions showing giant yeast forms of Blastomyces dermatitidis},
  author={Karen Walker and Henry G. Skelton and Kathleen J. Smith},
  journal={Journal of Cutaneous Pathology},
Background: The yeast forms of Blastomyces dermatitidis usually range from 8 to 15–20 µm in diameter. Larger yeast forms have previously been reported only twice in immunosuppressed patients. In both patients these large forms were seen within the lung. 

Blastomycosis in solid organ transplant recipients

Abstract: Background. Blastomyces dermatitidis, the etiologic agent of blastomycosis, causes severe disease and substantial mortality in those immunocompromised by acquired immunodeficiency syndrome

Secondary Intracerebral Blastomycosis with Giant Yeast Forms

A case of recurrent intracerebral blastomycosis that presented histopathologically with giant yeast-like cells and multinucleation that mimicked Coccidioides immitis is reported.

New Developments in Blastomycosis.

Infection with B. dermatitidis causes a broad array of clinical manifestations ranging from asymptomatic infection to fulminant sepsis with acute respiratory distress syndrome and death.

Antifungal Susceptibility of Candida Species and Cryptococcus Neoformans Isolated from Patients at the Komfo Anokye Teaching Hospital in Kumasi

A Thesis submitted to the Department of Clinical Microbiology,Kwame Nkrumah University of Science and Technology in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCE, School

Subcutaneous and Deep Mycoses

Invasive aspergillosis is the most common opportunistic fungal infection in the hematopoetic stem cell transplant patient. Prior to the regular use of antifungal prophylaxis, invasive fungal

Northern Wisconsin married couple infected with blastomycosis.

  • J. BachirG. Fitch
  • Medicine
    WMJ : official publication of the State Medical Society of Wisconsin
  • 2006
2 cases of blastomycosis originating in a husband and wife who were both symptomatic and diagnosed with blastomyCosis within 4 months of each other are reported, one presented with pulmonary symptoms, the other with cutaneous symptoms.

Candida species associated with urinary tract infections

The key to managing candidemia episodes is early diagnosis and appropriate therapy, and the use of broad-spectrum antibiotics, cancer treatment, Candida species colonization of mucosal surfaces and broad- spectrum use antifungal.

Endemic Mycoses After Hematopoietic Stem Cell or Solid Organ Transplantation

For the initial treatment of most transplant recipients, lipid formulation amphotericin B is preferred and long-term suppressive azole therapy may be indicated for those patients who remain markedly immunosuppressed.

Evaluation of Antifungal Susceptibility Profile of Candida Species Isolated from Female Patients Attending Aminu Kano Teaching Hospital (AKTH)

The study was aimed at evaluating the antifungal susceptibility profile of Candida species isolated from female patients attending Aminu Kano Teaching Hospital (AKTH), with suspected Candidal infections August, 2012 to June, 2013.



Blastomyces dermatitidis with large yeast forms.

A rare case of primary pulmonary blastomycosis with an unusual morphology is reported, in which significant numbers of large yeast forms ranging from 30 to 35 microm in diameter are found.

Giant forms of Blastomyces dermatitidis in the pulmonary lesions of blastomycosis. Potential confusion with Coccidioides immitis.

Typical yeast-phase cells of Blastomyces dermatitidis have a characteristic appearance in tissue sections, in which some of the yeast-like cells were abnormally large, and coccidioidomycosis was considered initially in the differential diagnosis.

Systemic fungal infections: diagnosis and treatment. I. Blastomycosis.

  • R. Bradsher
  • Medicine
    Infectious disease clinics of North America
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The features of blastomycosis that relate to the clinical practice of medicine are reviewed and therapeutic options include treatment with amphotericin B or ketoconazole, or simple observation if spontaneous resolution is anticipated.

Blastomycosis in the immunocompromised patient.

  • P. Pappas
  • Medicine, Biology
    Seminars in respiratory infections
  • 1997
Clinically, the disease in immunocompromised patients with blastomycosis is potentially much more severe and is characterized by disseminated multiple organ involvement including frequent involvement of the central nervous system.

Isolation of Blastomyces dermatitidis in soil associated with a large outbreak of blastomycosis in Wisconsin.

It is concluded that B. dermatitidis in the soil can be a reservoir for human infection and isolated Blastomyces dermat itidis from soil at a beaver pond near the camp in northern Wisconsin in June 1984.

Blastomycosis in Immunocompromised Patients

The data presented herein suggest that blastomycosis may occur more commonly in immunocompromised patients than was previously recognized, and oral therapy with an azole compound should probably be reserved for patients who have responded to a primary course of amphotericin B but who require additional or long-term suppressive therapy.

Development of specific immunity in patients with pulmonary or extrapulmonary blastomycosis.

  • R. Bradsher
  • Medicine, Biology
    The American review of respiratory disease
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Lymphocyte stimulation does not appear helpful for diagnosis of persons with untreated pulmonary blastomycosis, but in vitro correlates of cellular immunity developed in these patients in a similar time course as with other chronic infections.

Basic sérodiagnostic methods for diseases caused by fungi and actinomycetes.

This inexpensive manual, designed for practice in the United Kingdom, is an excellent addition to the Public Health Laboratory Service Monograph Series, and should have a wide circulation.

Blastomycosis. A review of 152 cases.