Cutaneous iontophoresis of treprostinil, a prostacyclin analog, increases microvascular blood flux in diabetic malleolus area.

@article{Hellmann2015CutaneousIO,
  title={Cutaneous iontophoresis of treprostinil, a prostacyclin analog, increases microvascular blood flux in diabetic malleolus area.},
  author={Marcin Hellmann and Matthieu Roustit and Florence Gaillard-Bigot and J. L. Cracowski},
  journal={European journal of pharmacology},
  year={2015},
  volume={758},
  pages={
          123-8
        }
}
Diabetic foot ulcers are one of the most common and serious complications of diabetes mellitus. Few drugs are effective in enhancing the healing of microvascular skin ulcers. The main objective of the present study was to determine whether iontophoresis of treprostinil, a prostacyclin analog, increases skin microvascular blood flux in the malleolus area of healthy subjects and diabetic patients. We recruited 12 healthy subjects and 12 type 2 diabetic patients. Cathodal iontophoresis (40mC/cm… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-6 OF 6 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 24 REFERENCES

Trials and tribulations of skin iontophoresis in therapeutics.

  • British journal of clinical pharmacology
  • 2014
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…