Cutaneous desmoplastic melanoma: reappraisal of morphologic heterogeneity and prognostic factors.

@article{Busam2004CutaneousDM,
  title={Cutaneous desmoplastic melanoma: reappraisal of morphologic heterogeneity and prognostic factors.},
  author={Klaus J. Busam and Urvi J. Mujumdar and Amanda J. Hummer and Jennifer Nobrega and W. G. Hawkins and Daniel G. Coit and Mary S Brady},
  journal={The American journal of surgical pathology},
  year={2004},
  volume={28 11},
  pages={1518-25}
}
Desmoplastic melanoma (DM) is a variant of melanoma, which may be confused with nonmelanocytic benign or malignant spindle cell proliferations. The histologic hallmark of DM is the presence of fusiform melanocytes dispersed in a prominent collagenous stroma. Phenotypic heterogeneity of DM is underrecognized. Desmoplasia may be prominent throughout the entire tumor ("pure" DM) or represent a portion of an otherwise nondesmoplastic melanoma ("combined" DM). We reviewed melanomas with desmoplasia… CONTINUE READING