• Corpus ID: 57753307

Cutaneous changes in chronic kidney disease patients on maintenance hemodialysis visiting at tertiary care hospital, Karachi

  title={Cutaneous changes in chronic kidney disease patients on maintenance hemodialysis visiting at tertiary care hospital, Karachi},
  author={Muhammad Ishaque Sonija and Pooran Mal and Dileep Kumar and Abdul Mannan Junejo},
  journal={Journal of Pakistan Association of Dermatology},
Objective To determine the frequency of cutaneous changes in patients with chronic kidney disease on maintenance hemodialysis. Methods A cross-sectional study conducted at Department of Nephrology, Jinnah Postgraduate Medical Centre, Karachi from 1 st August 2009 to 31 st January 2010. A total of 100 patients with chronic kidney disease on maintenance hemodialysis were included. After taking demographic data, cutaneous changes were noted. Mean and standard deviation were computed for… 
1 Citations

Tables from this paper


Frequency of anemia increases with the progression of stage of chronic kidney disease (decreased GFR) and anemia was mostcommon in stage 5 patients of Chronic kidney disease.



Cutaneous manifestations of chronic renal failure

Chronic renal failure is associated with complex array of cutaneous manifestations caused either by disease or treatment, the commonest are xerosis, pruritus, half-and-half nails and xerostomia.

Cutaneous manifestations in patients with chronic renal failure on hemodialysis.

The most prevalent finding was xerosis, followed by pallor, pruritus and cutaneous pigmentation, and the early recognition of cutaneous signs can relieve suffering and decrease morbidity among patients with CRF undergoing hemodialysis.

Dermatological Manifestations in Chronic Renal FailurePatients on Haemodialysis

There is a high prevalence of cutaneous changes in patients undergoing haemodialysis, with at least one cutaneous change found in 96% of patients.

Dermatological disorders in chronic kidney disease with and without maintenance hemodialysis.

Dermatological disorders were present in all CKD patients with significantly lower nail and hair changes in MHD, and a further longitudinal study is necessary to find out pathophysiology and effect of treatment in these disorders.

Pattern of skin and nail changes in chronic renal failure in Nepal: A hospital‐based study

The skin and nail changes were common in chronic renal failure and manifested in various forms and thorough inspection of the integument might reveal markers of occult renal disease.

Dermatologic manifestations in patients of renal disease on hemodialysis

Clinicians are familiarized about thedermatologic changes in patients with chronic renal failure (CRF) undergoing hemodialysis and on long-term hemodialysis to highlight cutaneous changes of diseases associated with the development of ESRF.

Optimal dialysis improves uremic pruritus.

Is aluminum toxicity responsible for uremic pruritus in chronic hemodialysis patients?

The findings suggest that prolonged exposure to aluminum in patients with chronic renal failure might be involved in the pathogenesis of uremic pruritus and elevated calcium-phosphate product seems to be an additional factor predisposing toPruritus.

Relief of pruritus and decreases in plasma histamine concentrations during erythropoietin therapy in patients with uremia.

Therapy with erythropoietin induced a decrease in plasma histamine concentrations in both groups of patients with uremia, and recurrences of pruritus after the discontinuation of erythrooiet in were accompanied by increases in plasma Histamine concentrations.

Skin signs of systemic diseases.