Cutaneous and systemic responses during primary and challenge infestations of sheep with the sheep scab mite, Psoroptes ovis

@article{Broek2000CutaneousAS,
  title={Cutaneous and systemic responses during primary and challenge infestations of sheep with the sheep scab mite, Psoroptes ovis},
  author={M. van den Broek and Huntley and Machell and Taylor and Bates and Groves and Miller},
  journal={Parasite Immunology},
  year={2000},
  volume={22}
}
Lesional area was estimated and lesional mast cells and eosinophils were counted during primary and challenge infestations of sheep with Psoroptes ovis. In addition, circulating basophils and eosinophils and serum P. ovis‐specific immunoglobulin IgE antibody were quantified. Expansion of lesional area was significantly less and serum IgE titres significantly greater in challenge than primary infestations. Lesional mast cell hyperplasia and massive eosinophil infiltration accompanied by raised… 
Infestation of sheep with Psoroptes ovis, the sheep scab mite, results in recruitment of Foxp3+ T cells into the dermis
TLDR
It is demonstrated that infestation of sheep with P. ovis results in an influx of Foxp3+ T cells into the skin, and it is hypothesized that Tregs are involved in sheep scab lesions and Treg responses may crucially affect lesion development and subsequent mite survival.
Dermal immune responses against Psoroptes ovis in two cattle breeds and effects of anti-inflammatory dexamethasone treatment on the development of psoroptic mange
TLDR
Results suggest that a stronger Th2-type immune response to P. ovis causes the skin lesions in psoroptic mange in BB cattle and that local anti-inflammatory treatment could potentially be an alternative to control the pathology caused by this parasite.
Identification of an antigen from the sheep scab mite, Psoroptes ovis, homologous with house dust mite group I allergens
TLDR
In enzyme‐linked immunosorbent assays, a pronounced IgG‐antibody response to Pso o 1 was detected in five of five sheep 3 weeks postinfestation, and a marked IgE response occurred in the fifth animal, and IgE anti Pso mite allergens were detected in the serum.
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