Cutaneous Molt Induced by Calciphylaxis in the Rat

  title={Cutaneous Molt Induced by Calciphylaxis in the Rat},
  author={H. Selye and G. Gentile and P. Prioreschi},
  pages={1876 - 1877}
A molt, conducive to the loss and subsequent replacement of all cutaneous layers, can be induced by topical "calciphylaxis" in the rat. This is accomplished by sensitization with dihydrotachysterol followed by challenge with egg white or ferric dextran. 
Calcific Uremic Arteriolopathy Revisited.
Calciphylaxis was first described in the early 1960s by dermatologist Hans Selye et al. [1][1] as local cutaneous calcification leading to inflammation and skin sclerosis, which is provoked by aExpand
A case of calciphylaxis and acute myeloid leukemia: A previously unreported association
The first known case of diffuse calciphylaxis associated with acute myeloid leukemia resulting in death from hypoxic respiratory failure and refractory hypotension is reported. Expand
Calciphylaxis: a systematic review of existing and emerging therapies.
Calciphylaxis is a cutaneous ischemic small vessel vasculopathy seen in 1 to 4% of patients with chronic kidney disease on hemodialysis and is associated with extreme pain and a 60 to 80% mortality rate in the setting of few and frequently ineffective therapeutic options. Expand
Nonuremic calciphylaxis triggered by rapid weight loss and hypotension.
A case of nonuremic calciphylaxis (NUC) occurring in the setting of multiple risk factors, including chronic corticosteroid use, obesity, rapid weight loss, and hypotension is reported. Expand
Siderocalciphylactic sensitization to distilled water.
Calciphylaxis is a condition of induced systemic hypersensitivity in which, during a "critical period" after sensitization by a systemic calcifying factor, treatment with certain challengers causes an acute local calcification followed by inflammation and sclerosis. Expand
Calciphylaxis — pathogenesis and clinical picture
An overview of the most important pathophysiological phenomena which accompany calciphylaxis is shown, which characterizes the clinical picture of the disease and presents available approaches to therapeutic management. Expand
Calciphylaxis Presenting with Various Symptoms: A Case Report
A patient with a case of calciphylaxis associated with a wide range of symptoms, including lower thigh skin ulcers, a rectovaginal fistula, and femoral neck fracture, underwent multiple treatments and eventually died of cardiac failure. Expand
The Koebner phenomenon may contribute to the development of calciphylaxis: A case series
Characteristics of patients who presented with calciphylaxis in areas of trauma are identified, suggesting the presence of Koebnerization. Expand
Calciphylaxis: Controversies in Pathogenesis, Diagnosis and Treatment
The purpose of this review is to summarize and analyze the currently available literature regarding the pathophysiology, risk factors, clinical presentation, diagnostic features and treatment modalities for this exceptionally uncommon illness. Expand
Painful skin ulcers in a hemodialysis patient.
  • S. Sprague
  • Medicine
  • Clinical journal of the American Society of Nephrology : CJASN
  • 2014
Treatment strategies for calciphylaxis are limited by inadequate understanding of its pathophysiology, and generally results in improvement of pain and healing of the lesions within 2-4 weeks, but the disorder generally takes many months to completely resolve. Expand


Allergy antd A pp1
  • Immnunol. 15,
  • 1961
Ferric dextran (Imferon
    This work was supported by the GustavuLs and Louise Pfeiffer Research Foundation and by the Office of the Surgeon General
    • Army Medical and Research Command, contract