Custom-fit radiolucent cranial implants for neurophysiological recording and stimulation

  title={Custom-fit radiolucent cranial implants for neurophysiological recording and stimulation},
  author={Grant H. Mulliken and N. Bichot and Azriel Ghadooshahy and J. Sharma and R. Desimone},
  journal={Journal of Neuroscience Methods},
  • Grant H. Mulliken, N. Bichot, +2 authors R. Desimone
  • Published 2015
  • Biology, Medicine
  • Journal of Neuroscience Methods
  • BACKGROUND Recording and manipulating neural activity in awake behaving animal models requires long-term implantation of cranial implants that must address a variety of design considerations, which include preventing infection, minimizing tissue damage, mechanical strength of the implant, and MRI compatibility. NEW METHOD Here we address these issues by designing legless, custom-fit cranial implants using structural MRI-based reconstruction of the skull and that are made from carbon… CONTINUE READING

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