Custom-fit radiolucent cranial implants for neurophysiological recording and stimulation

  title={Custom-fit radiolucent cranial implants for neurophysiological recording and stimulation},
  author={Grant H. Mulliken and Narcisse P. Bichot and Azriel Ghadooshahy and Jitendra Sharma and Simon Kornblith and Michael Philcock and Robert Desimone},
  journal={Journal of Neuroscience Methods},
BACKGROUND Recording and manipulating neural activity in awake behaving animal models requires long-term implantation of cranial implants that must address a variety of design considerations, which include preventing infection, minimizing tissue damage, mechanical strength of the implant, and MRI compatibility. NEW METHOD Here we address these issues by designing legless, custom-fit cranial implants using structural MRI-based reconstruction of the skull and that are made from carbon… CONTINUE READING

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