Curvature of designed armadillo repeat proteins allows modular peptide binding.

@article{Hansen2018CurvatureOD,
  title={Curvature of designed armadillo repeat proteins allows modular peptide binding.},
  author={Simon Hansen and Patrick Ernst and Sebastian L. B. K{\"o}nig and Christian Reichen and Christina Ewald and Daniel Nettels and Peer R. E. Mittl and Benjamin Schuler and Andreas Pl{\"u}ckthun},
  journal={Journal of structural biology},
  year={2018},
  volume={201 2},
  pages={108-117}
}
Designed armadillo repeat proteins (dArmRPs) were developed to create a modular peptide binding technology where each of the structural repeats binds two residues of the target peptide. An essential prerequisite for such a technology is a dArmRP geometry that matches the peptide bond length. To this end, we determined a large set (n=27) of dArmRP X-ray… CONTINUE READING