Current views on scorpion toxins specific for K+-channels.

  title={Current views on scorpion toxins specific for K+-channels.},
  author={Ricardo C Rodr{\'i}guez de la Vega and Lourival Domingos Possani},
  journal={Toxicon : official journal of the International Society on Toxinology},
  volume={43 8},
Much of our knowledge on K+-channels was elucidated using specific peptide ligands isolated from a number of venomous organisms. Recently, this field received a strong support and increased interest due to the solution of the three-dimensional structure of a couple of K+-channels. At the same time, several new subfamilies of specific toxins for K+-channels were isolated from scorpion venoms, enhancing the availability and diversity of such useful molecular tools. It opened new lines of research… CONTINUE READING