Current view and perspectives in amyotrophic lateral sclerosis

  title={Current view and perspectives in amyotrophic lateral sclerosis},
  author={St{\'e}phane Mathis and Philippe P Couratier and Adrien Julian and Philippe Corcia and Gwendal Le Masson},
  booktitle={Neural regeneration research},
Amyotrophic lateral sclerosis (ALS), identified as a distinct clinical entity by Charcot since the end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that affects motor neurons in the brain, brainstem and spinal cord. Survival of patients with ALS is associated with several factors such as clinical phenotype, age at onset, gender, early presence of respiratory failure, weight loss and treatment with Riluzole (the only disease-modifying drug approved for this… CONTINUE READING


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