Current understanding of the application of pyridinium oximes as cholinesterase reactivators in treatment of organophosphate poisoning.

@article{Jokanovi2006CurrentUO,
  title={Current understanding of the application of pyridinium oximes as cholinesterase reactivators in treatment of organophosphate poisoning.},
  author={Milan Jokanovi{\'c} and Milos P. Stojiljkovic},
  journal={European journal of pharmacology},
  year={2006},
  volume={553 1-3},
  pages={10-7}
}
This paper reviews the mechanisms of interaction of organophosphorus compounds with cholinesterases and clinical signs of acute poisoning. Further, we describe the current understanding of the mechanisms of action of pyridinium oximes pralidoxime (PAM-2), trimedoxime (TMB-4), obidoxime (LüH-6, Toxogonin), HI-6 and HLö-7 which are used as cholinesterase… CONTINUE READING