Current understanding of conventional outflow dysfunction in glaucoma.

  title={Current understanding of conventional outflow dysfunction in glaucoma.},
  author={William Daniel Stamer and Ted S. Acott},
  journal={Current opinion in ophthalmology},
  volume={23 2},
PURPOSE OF REVIEW Regulation of intraocular pressure by the conventional (trabecular) outflow pathway is complicated, involving a myriad of mechanical and chemical signals. In most, intraocular pressure is maintained within a tight range over a lifetime. Unfortunately in some, dysfunction results in ocular hypertension and open-angle glaucoma. In the context of established knowledge, this review summarizes recent investigations of conventional outflow function, with the goal of identifying… CONTINUE READING


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