Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs.

@article{Vo2013CurrentTA,
  title={Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs.},
  author={Chau Le-Ngoc Vo and Chulhun Park and Beom-Jin Lee},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  year={2013},
  volume={85 3 Pt B},
  pages={799-813}
}
Over 40% of active pharmaceutical ingredients (API) in development pipelines are poorly water-soluble drugs which limit formulation approaches, clinical application and marketability because of their low dissolution and bioavailability. Solid dispersion has been considered one of the major advancements in overcoming these issues with several successfully marketed products. A number of key references that describe state-of-the-art technologies have been collected in this review, which addresses… CONTINUE READING
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