Current treatment options in prolymphocytic leukemia.

  title={Current treatment options in prolymphocytic leukemia.},
  author={Tadeusz Robak and Paweł Robak},
  journal={Medical science monitor : international medical journal of experimental and clinical research},
  volume={13 4},
Prolymphocytic leukemia (PLL) is a rare lymphoproliferative disorder characterized by marked leukocytosis and splenomegaly. PLL accounts for approximately 2% of chronic lymphoid leukemias. The clinical course is progressive in the majority of cases due to the resistance of the disease to conventional chemotherapy. The disease is divided according to the cell of origin into the B- (B-PLL) and T-cell (T-PLL) types. T-PLL and B-PLL are morphologically identical, but lymphadenopathy and skin… CONTINUE READING
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