Current therapies to shorten postoperative ileus

@article{Johnson2009CurrentTT,
  title={Current therapies to shorten postoperative ileus},
  author={Michael D. Johnson and R. Matthew Walsh},
  journal={Cleveland Clinic Journal of Medicine},
  year={2009},
  volume={76},
  pages={641 - 648}
}
Postoperative ileus delays hospital discharge, increases costs, and contributes to adverse outcomes. A variety of neural and chemical factors are involved. To shorten the duration of postoperative ileus, we may need to establish standard plans of care that favor earlier feeding, use of nasogastric tubes only on a selective basis, and prokinetic drugs as needed. Rather than merely wait for bowel sounds to return after patients undergo surgery, we can try to get the gut working again sooner. 
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Role of alvimopan (entereg) in gastrointestinal recovery and hospital length of stay after bowel resection.
TLDR
GI recovery times were generally shorter for alvimopan-treated patients than for those who did not receive the study drug (P < 0.05), and this medication was considered to be a good choice for the perioperative management of patients requiring segmental bowel resection with primary anastomosis.
Íleo Paralítico Pós-operatório: Fisiopatologia, Prevenção e Tratamento
TLDR
The pathophysiology, prevention, and treatment of postoperative ileus are reviewed, with a focus on the treatment and management of the central nervous system disorder.
Risk factors for postoperative ileus
TLDR
This study confirmed that unnecessary analgesics use in patients with pain tolerance with non-steroid anti-inflammatory drugs, excessive small bowel manipulation, prolonged nasogastric catheter use have a direct negative effect on gastrointestinal motility.
Treating a patient with intractable paralytic ileus using thoracic epidural analgesia.
Impact of postsurgical opioid use and ileus on economic outcomes in gastrointestinal surgeries
TLDR
Use of opioids in patients who develop ileus following abdominal surgeries is associated with prolonged hospitalization, greater costs, and increased readmissions, and higher doses of opioids are associated with higher incidence of POI.
Effect of Osteopathic Manipulative Treatment on Incidence of Postoperative Ileus and Hospital Length of Stay in General Surgical Patients
TLDR
Osteopathic manipulative treatment applied after a major gastrointestinal operation is associated with decreased time to flatus and decreased postoperative hospital LOS.
Comparison of early versus late enteral feeding following gut anastomosis.
TLDR
In the wake of gut anastomosis, early oral feeding at 12hours is superior to delayed oral feeding after 72hours, in terms of mean time for return of bowel sounds and period of hospital stay.
Controlling postoperative ileus by vagal activation.
TLDR
The application of safe and easy to use antiinflammatory interventions, together with the current multimodal approach, could reduce postoperative ileus to an absolute minimum and shorten hospital stay.
Chewing gum for postoperative recovery of gastrointestinal function.
TLDR
Whether chewing gum after surgery hastens the return of gastrointestinal function is examined to examine and the influence of study quality, reviewers' methodological estimations and use of Enhanced Recovery After Surgery (ERAS) programmes is investigated.
Effect of Intraoperative Dexmedetomidine Infusion on Postoperative Bowel Movements in Patients Undergoing Laparoscopic Gastrectomy
TLDR
DEX facilitated bowel movements and reduced the length of hospital stay in patients undergoing laparoscopic gastrectomy and may be attributed to the sympatholytic and opioid-sparing effects of DEX.
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TLDR
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TLDR
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TLDR
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TLDR
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