Corpus ID: 5889195

Current status on the development and treatment of myopia.

@article{Cooper2012CurrentSO,
  title={Current status on the development and treatment of myopia.},
  author={Jeffrey S. Cooper and Erica Schulman and Nadine Jamal},
  journal={Optometry},
  year={2012},
  volume={83 5},
  pages={
          179-99
        }
}
This is a review of the current literature describing the effect of atropine, bifocals, and/or contact lenses on slowing the progression of myopia. Cumulative data from a number of studies have demonstrated atropine instilled once a day in myopic eyes resulted in a 90% average reduction of myopia progression, as compared to untreated eyes, i.e., from 0.50 D/year to 0.05 D/year. Pirenzepine, a muscarinic pharmacological agent, has a minimal effect on pupil size and accommodation, and it has been… Expand
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TLDR
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References

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Myopia: attempts to arrest progression
TLDR
Well conducted randomised clinical trials with large sample sizes and adequate follow up designed to evaluate treatments to retard the progression of myopia should be conducted, since the identification of an effective intervention may have a greater public health impact on the burden and morbidity from myopia than the few treatments currently available. Expand
Progression of myopia.
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TLDR
The data support the view that atropine therapy is associated with decreased progression of myopia and that beneficial effects remain after treatment has been discontinued. Expand
Further observations on use of atropine in the treatment of myopia.
TLDR
The data support the fact that children with low refractive errors may well have "functional myopia," as opposed to the "axial myopia" that characterizes the higher levels of myopia, which are the best candidates for using atropine to reduce or diminish myopia changes. Expand
Further observations on use of atropine in the treatment of myopia.
TLDR
The data support the fact that children with low refractive errors may well have "functional myopia," as opposed to the "axial myopia" that characterizes the higher levels of myopia, which are the best candidates for using atropine to reduce or diminish myopia changes. Expand
Effects of different concentrations of atropine on controlling myopia in myopic children.
TLDR
Treatment with 0.5% atropine was the most effective on controlling myopia; however, treatment with the control group showed significantly less myopic progression. Expand
Treatment options for myopia.
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TLDR
A review of treatment options for myopia will emphasize recent results from well-designed clinical studies and will suggest possible future therapies, such as atropine and pirenzepine, which may be more effective in subsets of myopic children. Expand
Atropine in ameliorating the progression of myopia in children with mild to moderate myopia: a meta-analysis of controlled clinical trials.
TLDR
0.5% and 1% atropine was demonstrated to be effective and safe to ameliorate myopia progression in childhood with low-to-moderate myopia. Expand
Reducing the progression of myopia with atropine: a long term cohort study of Olmsted County students.
TLDR
The data support the view that atropine therapy is associated with decreased progression of myopia and that beneficial effects remain after treatment has been discontinued. Expand
Interventions to retard myopia progression in children: an evidence-based update.
TLDR
Long-term large-scale double-masked randomized clinical trials, including cycloplegic refraction, are needed before any recommendations about interventions in clinical practice to prevent high myopia in myopic children are considered. Expand
Management of progressive school myopia with topical atropine eyedrops and photochromic bifocal spectacles.
TLDR
Atropine and bifocals are an appropriate, effective, and safe management for progressive school myopia; and probably also for pathological myopia. Expand
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