Current status of therapy of solid tumors: brain tumor therapy.

  title={Current status of therapy of solid tumors: brain tumor therapy.},
  author={Michael R. Zalutsky},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={46 Suppl 1},
Treatment of malignant brain tumors with conventional approaches is largely unsuccessful because curative doses generally cannot be delivered without excessive toxicity to normal brain. Radioimmunotherapy is emerging as an attractive alternative for glioma therapy because of the potential for more selectively irradiating tumor cells while sparing normal tissues. Several institutions are engaged in phase I and phase II trials investigating the therapeutic potential of monoclonal antibodies (mAbs… CONTINUE READING


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Astatine-211 labeled human/mouse chimeric anti-tenascin monoclonal antibody via surgically created resection cav ities for patients with recurrent glioma: Phase I study [abstract

  • M Zalutsky, D Reardon, G Akabani
  • Neuro-oncol
  • 2002
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