Current status of the therapy of advanced renal carcinoma.

@article{Hrushesky1977CurrentSO,
  title={Current status of the therapy of advanced renal carcinoma.},
  author={William J. M. Hrushesky and Gerald P. Murphy},
  journal={Journal of surgical oncology},
  year={1977},
  volume={9 3},
  pages={277-88}
}
A preclinical murine renal model system is available for evaluation of the effectiveness of therapeutic agents. Clinical review reveals that objective response rates to hormonal agents reported since 1971 have been substantially lower than those reported prior to 1971. Many chemotherapeutic agents have not been adequately evaluated clinically or with the experimental model. Vinblastine to date may be the most active single agent with a 25% objective response rate. At the present time, it is… CONTINUE READING

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