Current status of mucins in the diagnosis and therapy of cancer.

  title={Current status of mucins in the diagnosis and therapy of cancer.},
  author={Satyanarayana Rachagani and Maria Bella Palomo Torres and Nicolas Moniaux and Surinder Batra},
  volume={35 6},
Mucins are the most abundant high molecular weight glycoproteins in mucus. Their nature and glycosylation content dictates the biochemical and biophysical properties of viscoelastic secretions, pointing out an important role in diverse biological functions, such as differentiation, cell adhesions, immune responses, and cell signaling. Mucins are expressed in tubular organs by specialized epithelial cells in the body. Their aberrant expression is well documented in a variety of inflammatory or… CONTINUE READING

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Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes

  • V. Guyonnet Duperat, J. P. Audie, +7 authors N. Porchet
  • Biochem J
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