Current status of immunologic approaches to treating tobacco dependence: Vaccines and nicotine-specific antibodies

Abstract

In contrast to current pharmacotherapies, immunologic approaches to treating tobacco dependence target the drug itself rather than the brain. This approach involves the use of nicotine-specific antibodies that bind nicotine in serum, resulting in a decrease in nicotine distribution to the brain and an increase in nicotine's elimination half-life. This… (More)
DOI: 10.1208/aapsj080108

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