Current status of catheter- and stent-based gene therapy.

  title={Current status of catheter- and stent-based gene therapy.},
  author={Faisal Sharif and Kieran Daly and Jay Crowley and Timothy O'Brien},
  journal={Cardiovascular research},
  volume={64 2},
Significant progress has been made in the field of cardiovascular gene therapy over the past decade. Animal models of human disease have helped in identifying potential therapeutic genes and have also assisted in the evaluation of an ideal vector. A number of percutaneous catheter systems have been used in animal models with limited success. Stents represent an attractive alternative for localized gene delivery, as they provide a platform for prolonged gene elution and efficient transduction of… CONTINUE READING
18 Citations
77 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 18 extracted citations


Publications referenced by this paper.
Showing 1-10 of 77 references

Targeted gene delivery to vascular tissue in vivo by tropism-modified AAV vectors. Circulation 2004;109:513–9

  • SJ White, SA Nicklin, H Bqning
  • 2004
1 Excerpt

Effect of adeno-associated virus serotype on vascular gene delivery in vivo

  • S Sen, JS Bartlett, T O’Brien
  • Circulation 2003;108(No
  • 2003
1 Excerpt

Similar Papers

Loading similar papers…