Current status and challenges of antiretroviral research and therapy.

Abstract

Twenty-five years after the discovery of the therapeutic activity of azidothymidine (AZT), the first antiretroviral drug used in the clinic, infection with the human immunodeficiency virus (HIV) has become, at least in the industrialized world, a manageable chronic disease with a significant improvement in life expectancy and quality. Nevertheless, the… (More)
DOI: 10.1016/j.antiviral.2009.10.007

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