Current state of Marek's disease virus microRNA research.

  title={Current state of Marek's disease virus microRNA research.},
  author={Julie Ann Hicks and Hsiao-Ching Liu},
  journal={Avian diseases},
  volume={57 2 Suppl},
MicroRNA (miRNA) is a major family of small RNAs that posttranscriptionally regulate gene expression. Small RNA profiling studies have revealed that some viruses, particularly large DNA viruses, such as Marek's disease virus (MDV), encode their own set of miRNAs. There are currently 406 viral miRNAs in miRBase, of which 392 are encoded by herpesviruses. To date, 26 MDV-1 miRNAs, 36 MDV-2 miRNAs, and 28 herpesvirus of turkeys miRNAs have been identified. Interestingly, herpesvirus miRNAs appear… CONTINUE READING

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