Current role of liquid chromatography coupled to mass spectrometry in clinical toxicology screening methods.

@article{Viette2011CurrentRO,
  title={Current role of liquid chromatography coupled to mass spectrometry in clinical toxicology screening methods.},
  author={V{\'e}ronique Viette and Marc Fathi and Serge Laurent Rudaz and Denis Francois Hochstrasser and J. L. Veuthey},
  journal={Clinical chemistry and laboratory medicine},
  year={2011},
  volume={49 7},
  pages={
          1091-103
        }
}
Abstract Toxicological screening is the analysis of a biological specimen to detect and identify compounds in patients admitted to the hospital with acute intoxication of unknown origin. The screening of a wide range of toxicologically relevant compounds in biological samples is a serious challenge for clinical laboratories. The high selectivity and sensitivity of liquid chromatography coupled to mass spectrometry or tandem mass spectrometry technology provides an attractive alternative to the… CONTINUE READING
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