Current recommendations for chelation for transfusion-dependent thalassemia.

Abstract

Regular red cell transfusions used to treat thalassemia cause iron loading that must be treated with chelation therapy. Morbidity and mortality in thalassemia major are closely linked to the adequacy of chelation. Chelation therapy removes accumulated iron and detoxifies iron, which can prevent and reverse much of the iron-mediated organ injury. Currently… (More)
DOI: 10.1111/nyas.13088

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