Current progress and challenges in HIV gene therapy.

  title={Current progress and challenges in HIV gene therapy.},
  author={Janet Chung and John J. Rossi and Ulrike Jung},
  journal={Future virology},
  volume={6 11},
HIV-1 causes AIDS, a syndrome that affects millions of people globally. Existing HAART is efficient in slowing down disease progression but cannot eradicate the virus. Furthermore the severity of the side effects and the emergence of drug-resistant mutants call for better therapy. Gene therapy serves as an attractive alternative as it reconstitutes the immune system with HIV-resistant cells and could thereby provide a potential cure. The feasibility of this approach was first demonstrated with… CONTINUE READING

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