Current position of phenobarbital in epilepsy and its future

@article{Brodie2012CurrentPO,
  title={Current position of phenobarbital in epilepsy and its future},
  author={M. Brodie and P. Kwan},
  journal={Epilepsia},
  year={2012},
  volume={53}
}
  • M. Brodie, P. Kwan
  • Published 2012
  • Medicine
  • Epilepsia
  • This article reviews the current position of phenobarbital using articles published since 2000 and speculates on its likely future contribution to epilepsy care. Over the last decade there have been no major double‐blind randomized placebo‐controlled or comparative trials with phenobarbital. Previous studies have suggested that phenobarbital is as effective in monotherapy as phenytoin and carbamazepine. Several observational studies undertaken in developing countries over the last decade have… CONTINUE READING
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    References

    SHOWING 1-10 OF 65 REFERENCES
    Phenobarbital for childhood epilepsy: systematic review.
    • D. Pal
    • Medicine
    • Paediatric and perinatal drug therapy
    • 2006
    • 21
    • Highly Influential
    • PDF
    Side effects of phenobarbital in epilepsy: a systematic review
    • 39
    • PDF
    Phenobarbital for the Treatment of Epilepsy in the 21st Century: A Critical Review
    • 245
    Carbamazepine versus phenobarbitone monotherapy for epilepsy.
    • 53
    A randomized controlled trial of phenobarbital in neonates with hypoxic ischemic encephalopathy
    • D. Singh, P. Kumar, A. Narang
    • Medicine
    • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
    • 2005
    • 32
    Cognitive and mood effects of phenobarbital treatment in people with epilepsy in rural China: a prospective study
    • 16
    Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial
    • 46
    • PDF