Current perspectives on the impact of Kratom use

  title={Current perspectives on the impact of Kratom use},
  author={Charles A. Veltri and Oliver Grundmann},
  journal={Substance Abuse and Rehabilitation},
  pages={23 - 31}
Abstract The leaves from the tree Mitragyna speciosa, commonly known as Kratom, in the coffee plant family (Rubiaceae) are commonly used in their native habitat of Southeast Asia as a stimulant to sustain energy during hard day labor and as an opioid-like analgesic and sedative. Traditional and modern uses overlap based on the effects of the leaf extract which has also gained popularity in the United States and Europe in the last two decades. Kratom has and is being used for the mitigation of… 
Kratom (Mitragyna speciosa): worldwide issues.
PURPOSE OF REVIEW To inform readers about the increasingly popular Western dietary supplement, kratom (Mitragyna speciosa) and how the products are available in the Western world compared with
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A comprehensive overview of the available science on kratom is provided that has the potential to i clarity for healthcare providers and patients and makes recommendations for best practices in working with people who use kratom.
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A comprehensive narrative review of literature focusing on the psychoactive alkaloids of kratom, the possible neurobiological and pathophysiological models underlying the occurrence of k mitragynine dependence, and the clinical presentations and effective treatment options available for kratom dependence is provided.
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The case of a patient who developed anxiety and dysphoric mood and insomnia while using kratom, with these symptoms persisting after withdrawal, is described.
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Until studies are conducted that define kratom's role in treating opioid withdrawal and/or other central nervous system conditions, kratom will likely remain available as a dietary supplement for the foreseeable future.
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Update on the Pharmacology and Legal Status of Kratom
  • W. Prozialeck
  • Environmental Science
    The Journal of the American Osteopathic Association
  • 2016
This report highlights the current scientific and legal controversies regarding kratom and its mitragynine constituents, which prompted a massive response from kratom advocates.
Kratom policy: The challenge of balancing therapeutic potential with public safety
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Analyses of the medical literature and select Internet sites indicate that individuals in the United States are increasingly using kratom for the self-management of pain and opioid withdrawal.
A study of kratom eaters in Thailand.
Thirty male and female cases of kratom addiction were selected from the Nondhaburi province and from the suburbs of Bangkok for the purpose of an intensive study, and the interview method was used with a questionnaire consisting of 30 items.
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From Kratom to mitragynine and its derivatives: Physiological and behavioural effects related to use, abuse, and addiction
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To assess the impact of kratom in the United States, CDC analyzed overdose deaths in which kratom was detected on postmortem toxicology testing and deaths that were determined by a medical examiner or coroner to be a cause of death.
Following “the Roots” of Kratom (Mitragyna speciosa): The Evolution of an Enhancer from a Traditional Use to Increase Work and Productivity in Southeast Asia to a Recreational Psychoactive Drug in Western Countries
It is concluded that the use of kratom is not negligible, especially for self-medication, and more clinical, pharmacological, and socioanthropological studies as well as a better international collaboration are needed to tackle this marginally explored phenomenon.