Current perspectives in the management of hyponatremia: prevention of CPM.

@article{Sterns2007CurrentPI,
  title={Current perspectives in the management of hyponatremia: prevention of CPM.},
  author={Richard H. Sterns and Stephen M Silver and Betty K Kleinschmidt-Demasters and Amyn M Rojiani},
  journal={Expert review of neurotherapeutics},
  year={2007},
  volume={7 12},
  pages={1791-7}
}
Central pontine myelinolysis represents a relatively contemporary neurologic entity in which an imbalance of water relative to alterations in the body's electrolyte levels induces characteristic demyelination in the central part of the basis pontis as well as extrapontine sites. The clinical scenario is typically one of chronic hyponatremia followed by a rapid correction to normonatremic or hypernatremic levels. This seemingly innocuous series of events can result in fatal consequences. Better… CONTINUE READING